Mevalonate pathway

Streptococcus pneumonia use the mevalonate pathway for the synthesis of IPP .

在肺炎链球菌中，异戊二烯的合成主要采用甲羟戊酸途径。

Organizational Pathways of Transformation of Chinese Proactive Universities ; Study of Mevalonate Pathway in Cardiovascular System of Spontaneously Hypertensive Rats

我国自主创新型大学组织转型的途径&以华中科技大学为例自发性高血压大鼠心血管组织中甲羟戊酸途径的研究

These pleiotropic effects of Simvastatin might be partly mediated by its inhibition on the mevalonate pathway .

辛伐他汀降脂外作用部分是通过抑制内皮细胞甲基戊酸的合成而实现的。

The aim of this study was to explore the role of the mevalonate pathway and the isoprenoid pathway in the pathogenesis of schizophrenia .

以便进一步探讨产生异戊二烯的甲羟戊酸和类异戊二烯代谢通路及其代谢异常在精神分裂症病理生理机制中的作用。

Background : Farnesyl pyrophosphate synthase ( FPPS ), an essential enzyme in the mevalonate pathway , catalyzes the synthesis of isoprenoid intermediates . The latter is needed for isoprenylation of small GTPase .

背景：法呢醇焦磷酸合成酶（FPPS）是甲羟戊酸途径中的一个重要酶，能催化合成异戊二烯中间产物，而后者在小GTP蛋白异戊二烯化过程中不可或缺。

CONCLUSION : The proliferation of ASMCs induced by Ang ⅱ and PDGF was inhibited by fluvastatin , suggesting that mevalonate acid pathway may play an important role in the proliferation of ASMCs .

结论：氟伐他汀抑制AngⅡ和PDGF诱导的高血压大鼠血管平滑肌细胞增殖；甲羟戊酸代谢途径可能参与血管平滑肌细胞增殖过程。

Mevalonate ( Mev ) pathway plays a role in cell growth .

甲羟戊酸通路在细胞生长中起重要作用。

Products of mevalonate metabolism are critical for several celluar processes of eukaryotic cells , and inhibition of the mevalonate pathway by statins has pleiotropic effects .

甲羟戊酸的代谢产物是真核细胞一系列生物活动的关键，他汀类抑制甲羟戊酸代谢通路后可产生多种效应。